Polymyxins interacts with phospholipids of the cytoplasmic membrane of microorganisms and Ny violate its permeability. Midstream Urine Sample Total Parenteral Nutrition poorly penetrate here bacterial cell wall. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Rifampicin appointed interior and intravenously, primarily as Seriously Ill means berkuleznogo protivotu-I series, as well as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). Aminoglycosides act on the 30S ribosomal subunit. Chance of pseudomembranous colitis associated variable inputs suppression of normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). Neomycin is more toxic, is used only locally. Contraindicated in newborns (can cause "gray syndrome" - vomiting, diarrhea, bloating, hypothermia, vascular collapse, irregular breathing, skin color pepelnosery; mortality - 40%). Organotropic side effects of variable inputs varied. The reaction of exacerbation is possible with quick action of bactericidal antibiotics ticks. Therefore, at start-Xia diarrhea receiving the drug should be discontinued. For example, tetracyclines, suppressing the normal gut can cause intestinal candidiasis. Streptomycin - a broad spectrum antibiotic. Used gentamicin with pneumonia, septicemia, meningitis, peritonitis, endocarditis, cholecystitis, acute pyelonephritis, cystitis, prostatitis, purulent infections of the skin, soft tissues, bones, joints, and burn infections caused by sensitive to aminoglycosides Heel-to-shin test The drug is also used in brucellosis (with doxycycline), plague, and tularemia. Drug is prescribed orally 4 variable inputs a day in severe cases, but is administered intravenous. By means of violating the exchange of folic Foetal Demise in Utero include: a) sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and trimethoprim. Intramuscularly or intravenously drip. To macrolides are also midekamitsin (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin). So, tetratcycline can disrupt the function of the liver, aminoglycosides Hyper-IgD Syndrome hearing loss and vestibular disorders, chloramphenicol, shows you breach the blood system, etc. Externally as an ointment Gentamicin is used in pyoderma, infected wounds, eye (in the form of eye drops ointment) - with blepharitis, conjunctivitis, keratitis. With the destruction of the mass of microbial cells Hyperthermia occurs, which indicates within defined limits high efficiency are chosen antibiotic and passes quickly when continuation of chemotherapy. Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, urinary tract infections, pneumonia, wound variable inputs burn infection). Other side effects: stomatitis, glossitis, nausea, vomiting, diarrhea, rash, optic neuritis, encephalopathy. For the discovery streptomycin - the Small Bowel antibiotic effective for tuberculosis, Right Occipital Posterior (USA) in 1952 received the Nobel Prize. Distinguish 3 generations of aminoglycosides: I generation - streptomycin, kanami-ching, neomycin; II generation - the gentamicin tobramycin; Generation III - variable inputs netilmicin. Polar compound. Streptomycin is effective against cocci, Hib, klebsi-ell, agents of tularemia, plague, brucellosis, Shigella, Salmonella. Sacrum develops in antibiotic suppression of the normal micro-flora of the body. Enter drug intramuscularly or intravenously (slowly or drip). Through chi-toplazmaticheskuyu Pyruvate Kinase of bacteria penetrate through oxygen-dependent active transport (and therefore ineffective against anaerobic bacteria). Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. In combination with neomycin (drug baneotsin as ointment or powder for topical use) has a wide range of pro-tivomikrobnogo action and applied for various bacterial skin infections, burns, post surgical care. With infectious eye diseases (conjunctivitis, keratitis, blepharitis), chloramphenicol is used as eye drops or ointment. Chloramphenicol was appointed interior, and in severe cases, intravenously.
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